Factors affecting outcomes in Crohn's disease over 15 ...
Crohn's disease (CD) progression is marked by the occurrence of stricturing complications or intestinal and perianal penetrating complications, typically requiring surgery.1,2 We previously reported three factors at the time of diagnosis that increased the chance of disabling disease during the 5 years following: (1) age <40 years old, (2) presence of perianal lesions and (3) the …
Cancer Risk Among People With Type 1 and Type 2 Diabetes ...
There is now a large body of evidence indicating a strong and consistent increased risk of incident cancer associated with diabetes ().For type 2 diabetes, the strength of the association depends on the specific cancer site, with the strongest relationships observed for liver and pancreatic cancers, followed by endometrial, postmenopausal breast, colorectal, …
Egg consumption, cardiovascular diseases and type 2 ...
Am J Clin Nutr 2014; 100: 741–743. CAS Article Google Scholar 22. Senthong V, Li XS, Hudec T, Coughlin J, Wu Y, Levison B et al. Plasma trimethylamine N-oxide, a gut microbe–generated ...
Kiwifruit-derived supplements increase stool frequency in ...
They were also asked to avoid overseas travel for the period of the study because of the impact this may have on diet. Venous blood samples (~10 mL) were collected at the beginning and end of the study for biochemical analysis (Chem-20). ... Br J Nutr, 111 (2014), pp. 1945-1956. View Record in Scopus Google Scholar.
Consumption of sugar sweetened beverages, artificially ...
Objectives: To examine the prospective associations between consumption of sugar sweetened beverages, artificially sweetened beverages, and fruit juice with type 2 diabetes before and after adjustment for adiposity, and to estimate the population attributable fraction for type 2 diabetes from consumption of sugar sweetened beverages in the United States and United Kingdom.
Impaired Glucose Homeostasis in First-Episode ...
Br J Psychiatry. 2010;196(2):116-121. ... Given that several antipsychotic drugs may worsen glucose regulation, 63,64 there is thus a responsibility placed on the treating clinician to select an appropriate antipsychotic at an appropriate dose so as to limit the metabolic impact of treatment. Furthermore, the association between schizophrenia ...
A Prospective Study of Holiday Weight Gain | NEJM
Shimamoto H, Tanaka K, Adachi Y. Seasonal variation may have an effect on body composition alterations induced by exercise training. Jpn J Phys Fitness Sports Med 1998 ;47: 509 - …
Role of transporters in drug interactions | SpringerLink
Over the past few decades, a tremendous amount of work has been done on the molecular characterization of transport proteins in animals and humans, leading to a better understanding of the physiological roles of a number of transport proteins. Furthermore, there is increasing preclinical and clinical evidence to support the importance of transport proteins in …
All teas are not created equal: The Chinese green tea and ...
Of all the teas studied, green tea produces the highest level of antioxidant activity and black tea the lowest .Lee et al. also found the antioxidant capacity per serving of green tea (436 mg vitamin C equivalents) to be much higher than that of black tea (239 mg). Thus green tea possesses the strongest cardioprotective effects,, .The total catechin concentration in blood …
Medication-Assisted Treatment of Opioid Use Disorder ...
Opioid use disorder (OUD) is defined by the Diagnostic and Statistical Manual of Mental Disorders (fifth edition) 1 as the maladaptive use of opioids, prescribed or illicit, resulting in two or more criteria that reflect impaired health or function over a 12-month period. OUD is scaled according to severity (mild/moderate/severe) and does not require physiological tolerance or dependence in ...
Brief meditation training induces smoking reduction | PNAS
More than 5 million deaths a year are attributable to tobacco smoking, but attempts to help people either quit or reduce their smoking often fail, perhaps in part because the intention to quit activates brain networks related to craving. We recruited participants interested in general stress reduction and randomly assigned them to meditation training or a relaxation …
Potential role of cellular miRNAs in coronavirus-host ...
Zhou F, Yu T, Du R, Fan G, Liu Y, Liu Z, Xiang J, Wang Y, Song B, Gu X, Guan L, Wei Y, Li H, Wu X, Xu J, Tu S, Zhang Y, Chen H, Cao B. 2020a. Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study. Lancet 395 (10229): 1054-1062
Capsaicin may have important potential for promoting ...
Capsaicin, the phytochemical responsible for the spiciness of peppers, has the potential to modulate metabolism via activation of transient receptor potential vanilloid 1 (TRPV1) receptors, which are found not only on nociceptive sensory neurons, but also in a range of other tissues. TRPV1 activation induces calcium influx, and in certain tissues this is associated with …
Regulation of Immune Function by Polyphenols
Veerman JL, Healy GN, Cobiac LJ, et al. Television viewing time and reduced life expectancy: a life table analysis.Br J Sports Med 2012;46:927–30.This was published in the print issue with the incorrect doi 10.1136/bjsports-2011-085662. The correct doi is 10.1136/bjsm.2011.085662 because this is the doi it was originally published with Online First.
Antidiabetic and Antioxidant Effects of Apple Cider ...
Br. J. Pharmacol. 142, 231–255. First citation in article Google Scholar. Baynes, J. W. (1991) Role of oxidative stress in development of complications in diabetes. Diabetes 40, 405–412. First citation in article Google Scholar
John Robert Vane – Wikipedia tiếng Việt
Nổi tiếng vì. aspirin, prostaglandin. Giải thưởng. Giải Nobel Sinh lý và Y khoa năm 1982. Sự nghiệp khoa học. Ngành. Dược lý học. Sir John Robert Vane (29.3.1927 – 19.11.2004) là một nhà dược lý học người Anh, đã đoạt giải Nobel Sinh lý và Y khoa .
Wired to run: exercise-induced endocannabinoid signaling ...
The hypothesis that neurobiological rewards motivate human endurance exercise (Ekkekakis et al., 2005; Sher, 1998) is consistent with evidence that humans are highly adept endurance athletes (Bramble and Lieberman, 2004; Carrier, 1984).For example, humans possess anatomical specializations and demonstrate endurance athletic performance (e.g. speed and distance …
USP15 antagonizes CRL4CRBN-mediated ubiquitylation of ...
CRBN, a substrate receptor of CUL4-RBX1-DDB1-CRBN (CRL4CRBN) E3 ubiquitin ligase, is a direct target for thalidomide teratogenicity and antitumor activity of immunomodulatory drugs (IMiDs) in multiple myeloma (MM) and other hematologic malignancies. IMiDs bind CRBN to recruit neosubstrates for ubiquitylation and subsequent degradation. …
Estimates of all cause mortality and cause specific ...
Suzuki H, Matsuzaki J. Helicobacter pylori eradication failure may have confounded the recent large-scale health database study that showed proton pump inhibitors increase gastric cancer risk. Gut 2017; 67: 2071-2. doi: …
British Journal of Clinical Pharmacology - Wiley Online ...
The British Journal of Clinical Pharmacology is a leading international clinical pharmacology journal published by the British Pharmacological Society. It bridges the gap between the medical profession, clinical research and the pharmaceutical industry by addressing all aspects of drug action in humans: invited review articles, original papers and correspondence.
(PDF) The relationship between creativity and mood disorders
Br J Psychiatry. 1994;165:22-34. 10. Ludwig AM. Creative achievement and psychopathology: comparison ... The effect of lithium treatment on artistic …
Physical inactivity is associated with a higher risk for ...
Objectives To compare hospitalisation rates, intensive care unit (ICU) admissions and mortality for patients with COVID-19 who were consistently inactive, doing some activity or consistently meeting physical activity guidelines. Methods We identified 48 440 adult patients with a COVID-19 diagnosis from 1 January 2020 to 21 October 2020, with at least three exercise vital sign …
Sensitivity of the circadian system to evening bright ...
Thus, the 1-h before bedtime may represent a window during which the circadian system is sensitive to perturbations (i.e., suppression of melatonin and phase delays) (Khalsa et al. 2003). Recently published data demonstrate that adults are sensitive to the effects of electronic media use in the 1-h before bedtime (Chang et al. 2015 ).
IJMS | Free Full-Text | Citrange Fruit Extracts Alleviate ...
Obesity is becoming one of the global epidemics of the 21st century. In this study, the effects of citrange (Citrus sinensis × Poncirus trifoliata) fruit extracts in high-fat (HF) diet-induced obesity mice were studied. C57BL/6 mice were fed respectively a chow diet (control), an HF diet, HF diet supplemented with 1% w/w citrange peel extract (CPE) or 1% …
Physical exercise and executive functions in preadolescent ...
Purpose The goal of this meta-analysis was to aggregate available empirical studies on the effects of physical exercise on executive functions in preadolescent children (6–12 years of age), adolescents (13–17 years of age) and young adults (18–35 years of age). Method The electronic databases PubMed, EMBASE and SPORTDiscus were searched for relevant studies reporting …
A single portion of blueberry (Vaccinium corymbosum L ...
J. Liu, J. Wang, Y. Jin, H.J. Roething, M. Unverdoben Variability of peripheral arterial tonometry in the measurement of endothelial function in healthy men Clin Cardiol, 32 ( 2009 ), pp. 700 - 704
Residual Effects of THC via Novel Measures of Brain ...
Br J Pharmacol 160: 544–548. CAS Article PubMed PubMed Central Google Scholar Filbey FM, Aslan S, Calhoun VD, Spence JS, Damaraju E, Caprihan A et al (2014). Long-term effects of marijuana use ...
Correction | British Journal of Sports Medicine
Veerman JL, Healy GN, Cobiac LJ, et al. Television viewing time and reduced life expectancy: a life table analysis.Br J Sports Med 2012;46:927–30.This was published in the print issue with the incorrect doi 10.1136/bjsports-2011-085662. The correct doi is 10.1136/bjsm.2011.085662 because this is the doi it was originally published with Online First.
Acid valerenic – Wikipedia tiếng Việt
C 15 H 22 O 2: Khối lượng mol: 234.334: Điểm nóng chảy : Điểm sôi : Các nguy hiểm; Trừ khi có ghi chú khác, dữ liệu được cung cấp cho các vật liệu trong trạng thái tiêu chuẩn của chúng (ở 25 °C [77 °F], 100 kPa). ...
SARS-CoV-2 spike protein co-opts VEGF-A/neuropilin-1 ...
[66]. Zeng Y, Han H, Tang B, Chen J, Mao D, Xiong M. Transplantation of recombinant vascular endothelial growth factor (VEGF)189-Neural stem cells downregulates transient receptor potential vanilloid 1 (TRPV1) and improves motor outcome in spinal cord injury. Med Sci Monit 2018;24:1089–96.
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